MCQs AXSPA Blackboard Questions

Please answer with true or false to following statements on Axial Spondyloarthritis
Question 1

Which of these statements is TRUE?
Question 1*
- A. The most appropriate for monitoring Active or stable nr-Axial Spa is repeating MRI every 6 months.
- B. The longer use of NSAIDs in Axial Spa is safe and do not have increased CVS risk
- C. Inflammatory bowel disease, Gastroesophageal reflux, anterior uveitis and dactylitis are all expected associations of Axial Spondyloarthritis.
- D. In Axial Spa refractory to NSAID, csDMARDS or TNFi should be the next step of treatment
- E. Passive physical therapy modalities (massage or Ultrasonography) are most effective in patients with nr-SpA
Answer with a detailed explanation
C: Inflammatory bowel disease, Gastroesophageal reflux, anterior uveitis and dactylitis are all expected associations of Axial Spondyloarthritis.
Reference:
Dactylitis although infrequent but a recognised feature of Axial SpA (not only psoriatic arthritis) ASAS clinical features description
Your Answer is Incorrect
- Specific References: ASAS EULAR recommendations 2022
- A- Recommendation 2
Your Answer is Incorrect
- Specific References: ASAS EULAR recommendations 2022
B- Recommendation 5
Your Answer is Incorrect
- Specific References: ASAS EULAR recommendations 2022
D- Recommendation 8
Your Answer is Incorrect
- Specific References: ASAS EULAR recommendations 2022
E- Recommendation 4 Regular exercise (not passive massage)

Question 2

Q2 Which of these statements is TRUE?
Question 2*
- A. IL-17i are superior to TNFi in halting the progression of disease and reduce BME lesions.
- B. HLA B27 Positive in Axial SpA in more than 80% in all ethnic groups.
- C. Nr-SpA could progress to Axial Spa in around 50% in 3 years.
- D. In addition to morning stiffness and pain, fatigue is the most common additional symptoms.
- E. Leeds enthesitis score (LEI) is more comprehensive than SPARCC enthesitis score
- F. The response of nr-Spa to biologic therapy is better in women than men.
Answer with a detailed explanation
D. In addition to morning stiffness and pain, fatigue is the most common additional symptoms
Nr-Spa progress to Axial Spa around 15-30% in 2-5 in different studies
HLA B27 positivity can be more than 80% in european/ north american population, but is only about 20-40% in several Middle East studies.
IL17i and TNFi are comparable in the degree of radiological progression
SPARCC enthesitis score cover more points (18) compare to Leeds score (6)
Fatigue is part of regular assessment in clinical trials as features described by ASAS.
Your Answer is Incorrect
Specific References:
A- Recommendation 9ASAS EULAR recommendations 2022
Your Answer is Incorrect
Specific References:
- B- Geographical prevalence of family history in patients with axial spondyloarthritis and its association with HLA-B27 in the ASAS-PerSpA study, Anna Boel
Your Answer is Incorrect
Specific References:
C- Progression of patients with non-radiographic Axial Spondyloarthritis to axial spondyloarthritis: A POPULATION-BASED COHORT STUDY. Rushing Wang
Your Answer is Incorrect
Specific References:
E- Performance of 3 Enthesitis Indices in Patients with Peripheral Spondyloarthritis During Treatment with Adalimumab. Philip Mease.
Your Answer is Incorrect
Specific References:
- F- Gender Differences in Axial Spondyloarthritis: Women Are Not So Lucky. T Rusman

Step 1 of 2

Question 1

Which of these statements is TRUE?

Answer with a detailed explanation

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Question 2

Q2 Which of these statements is TRUE?

Answer with a detailed explanation

Your Answer is Incorrect

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