cTAK Blackboard Questions

Question 1
Which of the following clinical features is most commonly observed during the early (pre-vasculitic) phase of childhood-onset Takayasu arteritis?*
- A. Severe hypertension
- B. Congestive heart failure
- C. Prolonged fever, fatigue, weight loss
- D. Limb claudication or absent peripheral pulses
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Answer with Detailed explanation
C. Prolonged fever, fatigue, weight loss
Rationale: The pre-vasculitic phase of Takayasu arteritis often presents with non-specific systemic symptoms such as prolonged low-grade fever, fatigue, weight loss, and arthralgia before vascular signs appear.
Reference:
Ozen S, Pistorio A, Iusan SM, et al. EULAR/PRINTO/PRES criteria for Takayasu arteritis classification in children. Ann Rheum Dis. 2010;69(5):798-806. doi:10.1136/ard.2009.116657

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Question 1