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APLAR Grand Round Blackboard: Otseoarthritis in General Practice
Step
1
of
2
50%
Question 1
How many people are expected to live with osteoarthritis by 2050?
Question 1
*
A. Nearly 1 billion people
B. About 10 million people,
C. More than 5 billion people
D. Less than 50 million people.
Answer with a detailed explanation
A. Nearly 1 billion people
Reference
Steinmetz JD, Culbreth GT, Haile LM, Rafferty Q, Lo J, Fukutaki KG, Cruz JA, Smith AE, Vollset SE, Brooks PM, Cross M. Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet Rheumatology. 2023 Sep 1;5(9):e508-22.
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Question 2
What is the incidence of multimorbidity in patients with osteoarthritis?
Question 2
*
A. About 30%
B. Less than 50%
C. About 60%
D. About 25%
Answer with a detailed explanation
C. About 60%
Reference
Watt FE, Wise EM. Osteoarthritis and associated comorbidities: new answers and more questions. Rheumatology. 2021 Sep 1;60(9):3966-8.
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Question 3
Which joint structure is not typically affected by OA?
Question 3
*
A. Articular cartilage
B. Subchondral bone
C. Ligaments
D. Tendons
Answer with a detailed explanation
D. Tendons
Reference
Salman LA, Ahmed G, Dakin SG, Kendrick B, Price A. Osteoarthritis: a narrative review of molecular approaches to disease management. Arthritis Research & Therapy. 2023 Feb 18;25(1):27.
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Question 4
What is the primary enzyme responsible for the degradation of cartilage in osteoarthritis?
Question 4
*
A. Collagenase
B. Stromelysin
C. Gelatinase
D. Matrix metalloproteinases (MMPs)
Answer with a detailed explanation
D. Matrix metalloproteinases (MMPs)
Reference
Salman LA, Ahmed G, Dakin SG, Kendrick B, Price A. Osteoarthritis: a narrative review of molecular approaches to disease management. Arthritis Research & Therapy. 2023 Feb 18;25(1):27.
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Question 5
Which of the following is not a recommended non-pharmacologic treatment for osteoarthritis?
Question 5
*
A. Exercise
B. Tai chi
C. Cognitive behavior therapy
D. Transcutaneous electrical nerve stimulation
Answer with a detailed explanation
D. Transcutaneous electrical nerve stimulation
Reference
Kolasinski SL, Neogi T, Hochberg MC, Oatis C, Guyatt G, Block J, Callahan L, Copenhaver C, Dodge C, Felson D, Gellar K. 2019 American College of Rheumatology/Arthritis Foundation guideline for the management of osteoarthritis of the hand, hip, and knee. Arthritis & rheumatology. 2020 Feb;72(2):220-33.
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