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Feb 23, 2023 9:39 am
Reference - EULAR text book
Key characteristics of steroid myopathy include;
- Worsening of proximal muscle weakness—predominantly in the lower extremities
- Creatine kinase levels improved or normal
- Improvement with reduction of glucocorticoid dose
- No signs of active myositis on electromyography or MRI
- Selective atrophy of type II muscle fibres
- Increased urinary creatinine excretion
- Obvious extra muscular signs of glucocorticoid use: Cushing features
- Worsening of neck flexor weakness is an indicator of active myositis